THE POLYMER SOCIETY OF KOREA

연구논문 초록집

초록 검색

세션명 대학원생 구두발표 (I)
발표장 제10회장
논문코드 1O10-10
발표일 2021-10-21
발표시간 16:25-16:40
논문제목 NIR-Responsive poly(N-isopropylacrylamide-co-acrylic acid)/Prussian Blue Nanocomposite as a Potential Drug Delivery System
발표자 김시현
발표자 소속 충남대학교
저자 김시현, 이택승
소속 충남대학교
논문초록 Photo-responsive hydrogels are ideal candidates for applications in drug delivery systems due to their minimal invasiveness and potential for remote control. Therefore, many thermal-responsive hydrogels have been combined with photothermal agents. In this study, thermosensitive poly(N-isopropylamide-co-acrylic acid) was fabricated as a drug carrier and Prussian blue (PB) as a photothermal agent (microgel@PB). When microgel was irradiated with an 808 nm laser, PB could absorb NIR light and transform light into heat. Then, the heat was transferred to the thermal-responsive microgel, which caused the lower critical solution temperature phase transition. As a result, microgel@PB could release the drug by shrinking and able to apply as a potential druge delivery system in response to NIR light.